Transcendental Meditation

Study on stress and hormone levels

Effects of the Transcendental Meditation program on adaptive mechanisms: changes in hormone levels and responses to stress after 4 months of practice

Authors:  MacLean, C.R.; Walton, K.G.; Wenneberg, S.R.; Levitsky, D.K.; Mandarino, J.P.; Waziri, R.; Hillis, S.L.; Schneider, R.H.

research study hormones stress meditationMethods

Stress has been implicated in both somatic and mental disorders.

The mechanisms by which stress leads to poor health are largely unknown. However, studies in animals suggest that chronic stress causes high basal cortisol and low cortisol response to acute stressors and that such changes may contribute to disease.

Previous studies of the Transcendental Meditation (TM) technique as a possible means of countering effects of stress have reported altered levels of several hormones both during the practice and longitudinally after regular practice of this technique.

In this project, random assignment study, changes in baseline levels and acute responses to laboratory stressors were examined for four hormones – cortisol, growth hormone, thyroid-stimulating hormone and testosterone – before and after 4 months of either the Transcendental Meditation technique or a stress education control condition. At pre- and post-test, blood was withdrawn continuously through an indwelling catheter, and plasma or serum samples were frozen for later analysis by radioimmunoassay.


The results showed significantly different changes for the two groups, or trends toward significance, for each hormone over the 4 months.

In the Transcendental Meditation group, but not in the controls, basal cortisol level and average cortisol across the stress session decreased from pre- to post-test. Cortisol responsiveness to stressors, however, increased in the Transcendental Meditation group compared to controls.

The baselines and/or stress responsiveness for thyroid-stimulating hormone and growth hormone changed in opposite directions for the groups, as did the testosterone baseline.

Overall, the cortisol and testosterone results appear to support previous data suggesting that repeated practice of the Transcendental Meditation technique reverses effects of chronic stress significant for health. The observed group difference in the change of growth hormone regulation may derive from the cortisol differences, while the thyroid-stimulating hormone results are not related easily to earlier findings on the effects of chronic stress.

Academic reference:
Psychoneuroendocrinology, 1997 May; issue 22(4), pp 277-95.

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